Apoptosis Inhibitor 5 antibody

Catalog No. ABIN7001009

Product Details anti-Apoptosis Inhibitor 5 Antibody

Target: Apoptosis Inhibitor 5 (API5)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Apoptosis Inhibitor 5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human API5

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Apoptosis Inhibitor 5

Target: Apoptosis Inhibitor 5 (API5)

Alternative Name: API5 (API5 Products)

Synonyms: AAC-11 antibody, AAC11 antibody, AI196452 antibody, api5l1 antibody, sr:nyz021 antibody, zgc:66211 antibody, wu:fb26c03 antibody, API-5B antibody, aac-11 antibody, aac11 antibody, api5 antibody, API-5A antibody, api5-A antibody, MGC83290 antibody, API5 antibody, apoptosis inhibitor 5 antibody, apoptosis inhibitor 5 S homeolog antibody, apoptosis inhibitor 5 L homeolog antibody, API5 antibody, Api5 antibody, api5 antibody, api5.S antibody, api5.L antibody

Background: This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Molecular Weight: 57 kDa

NCBI Accession: NP_006586

UniProt: Q9BZZ5

Pathways: Growth Factor Binding