CX3CL1 antibody
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- Target See all CX3CL1 Antibodies
- CX3CL1 (Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1))
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CX3CL1 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Synthetic peptide of human CX3CL1
- Isotype
- IgG
- Top Product
- Discover our top product CX3CL1 Primary Antibody
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- Application Notes
- IHC 1:25-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.3 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- CX3CL1 (Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1))
- Alternative Name
- CX3CL1 (CX3CL1 Products)
- Synonyms
- ABCD3 antibody, CX3CL1 antibody, DKFZp459K117 antibody, Cx3c antibody, Scyd1 antibody, ABCD-3 antibody, C3Xkine antibody, CXC3 antibody, CXC3C antibody, NTN antibody, NTT antibody, SCYD1 antibody, fractalkine antibody, neurotactin antibody, AB030188 antibody, AI848747 antibody, CX3C antibody, Cxc3 antibody, D8Bwg0439e antibody, ATP binding cassette subfamily D member 3 antibody, C-X3-C motif chemokine ligand 1 antibody, chemokine (C-X3-C motif) ligand 1 antibody, ABCD3 antibody, CX3CL1 antibody, Cx3cl1 antibody, Abcd3 antibody
- Background
- This gene encodes a large cytokine protein of 373 amino acids, it contains multiple domains and is the only known member of the CX3C chemokine family. It is also commonly known under the names fractalkine (in humans) and neurotactin (in mice).The polypeptide structure of CXC3L1 differs from the typical structure of other chemokines.CX3CL1 is produced as a long protein (with 373-amino acid in humans) with an extended mucin-like stalk and a chemokine domain on top. The mucin-like stalk permits it to bind to the surface of certain cells. However a soluble (90 kD) version of this chemokine has also been observed. Soluble CX3CL1 potently chemoattracts T cells and monocytes, while the cell-bound chemokine promotes strong adhesion of leukocytes to activated endothelial cells, where it is primarily expressed. CX3CL1 elicits its adhesive and migratory functions by interacting with the chemokine receptor CX3CR1. Its gene is located on human chromosome 16 along with some CC chemokines known as CCL17 and CCL22.
- NCBI Accession
- NP_002987
- UniProt
- P78423
- Pathways
- Synaptic Membrane
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