LOX antibody

Catalog No. ABIN7000900

Product Details anti-LOX Antibody

Target: LOX (Lysyl Oxidase (LOX))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LOX antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human LOX

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:25-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LOX

Target: LOX (Lysyl Oxidase (LOX))

Alternative Name: LOX (LOX Products)

Synonyms: LOX antibody, Xlox antibody, MGC146507 antibody, lox antibody, zgc:77447 antibody, AI893619 antibody, TSC-160 antibody, H-rev142 antibody, Rrg1 antibody, lysyl oxidase antibody, lysyl oxidase a antibody, lysyl oxidase L homeolog antibody, LOX antibody, lox antibody, loxa antibody, lox.L antibody, Lox antibody

Background: The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 47 kDa

NCBI Accession: NP_002308

UniProt: P28300

Pathways: SARS-CoV-2 Protein Interactome