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TNK2 antibody
TNK2
Reactivity: Human, Mouse, Rat
WB, ELISA, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-TNK2 Antibody
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Target
See all TNK2 Antibodies
TNK2
(tyrosine Kinase, Non-Receptor, 2 (TNK2))
Reactivity
All reactivities for TNK2 antibodies
Human, Mouse, Rat
Host
All hosts for TNK2 antibodies
Rabbit
Clonality
All clonalities for TNK2 antibodies
Polyclonal
Conjugate
All conjugates for TNK2 antibodies
This TNK2 antibody is un-conjugated
Application
All applications for TNK2 antibodies
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
Characteristics
Polyclonal Antibody
Purification
Affinity purification
Immunogen
Synthetic peptide of human TNK2
Isotype
IgG
Top Product
Discover our top product TNK2 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB 1:1000-1:5000, IHC 1:50-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.6 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for TNK2
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Target
TNK2
(tyrosine Kinase, Non-Receptor, 2 (TNK2))
Alternative Name
TNK2 (TNK2 Products )
Synonyms
ACK antibody, ACK-1 antibody, ACK1 antibody, p21cdc42Hs antibody, AW552477 antibody, Ack antibody, Cdgip antibody, Pyk1 antibody, ack1 antibody, ackb antibody, tnk2 antibody, tnk2b antibody, wu:fj16g04 antibody, zgc:154019 antibody, tyrosine kinase non receptor 2 antibody, tyrosine kinase, non-receptor, 2 antibody, tyrosine kinase, non-receptor, 1 antibody, TNK2 antibody, Tnk2 antibody, tnk1 antibody
Background
This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.
Molecular Weight
119 kDa
NCBI Accession
NP_005772
UniProt
Q07912
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