ELANH2 antibody, zgc:91981 antibody, si:dkey-177p2.11 antibody, si:dkey-177p2.12 antibody, EI antibody, LEI antibody, M/NEI antibody, MNEI antibody, PI-2 antibody, PI2 antibody, elanh2 antibody, lei antibody, m/nei antibody, mnei antibody, pi2 antibody, serpin peptidase inhibitor, clade B (ovalbumin), member 1 antibody, serpin family B member 1 antibody, serpin family B member 1 L homeolog antibody, SERPINB1 antibody, serpinb1 antibody, serpinb1.L antibody
Background
The protein encoded by this gene is a member of the serpin family of proteinase inhibitors. Members of this family maintain homeostasis by neutralizing overexpressed proteinase activity through their function as suicide substrates. This protein inhibits the neutrophil-derived proteinases neutrophil elastase, cathepsin G, and proteinase-3 and thus protects tissues from damage at inflammatory sites. Alternative splicing results in multiple transcript variants.