RGS1 antibody

Catalog No. ABIN7237642

Product Details anti-RGS1 Antibody

Target: RGS1 (Regulator of G-Protein Signaling 1 (RGS1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human RGS1

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RGS1

Target: RGS1 (Regulator of G-Protein Signaling 1 (RGS1))

Alternative Name: RGS1 (RGS1 Products)

Synonyms: 1R20 antibody, BL34 antibody, IER1 antibody, IR20 antibody, RGS1 antibody, 1r20 antibody, bl34 antibody, ier1 antibody, ir20 antibody, regulator of G protein signaling 1 antibody, regulator of G-protein signaling 1 antibody, regulator of G-protein signaling 1 S homeolog antibody, Regulator of G-protein signaling 1 antibody, RGS1 antibody, Rgs1 antibody, rgs1.S antibody, rgs1 antibody

Background: This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.

Molecular Weight: 24 kDa

UniProt: Q08116

Pathways: MAPK Signaling, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events