RGP4 antibody, SCZD9 antibody, AA004315 antibody, AA597169 antibody, ESTM48 antibody, ESTM50 antibody, regulator of G protein signaling 4 antibody, regulator of G-protein signaling 4 antibody, RGS4 antibody, Rgs4 antibody
Background
Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain.