PARP11 antibody

Catalog No. ABIN7237576

Product Details anti-PARP11 Antibody

Target: PARP11 (Poly (ADP-Ribose) Polymerase Family, Member 11 (PARP11))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PARP11 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human PARP11

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PARP11

Target: PARP11 (Poly (ADP-Ribose) Polymerase Family, Member 11 (PARP11))

Alternative Name: PARP11 (PARP11 Products)

Synonyms: 5330431N24Rik antibody, AI851877 antibody, ARTD11 antibody, HIN1L antibody, C12orf6 antibody, parp11 antibody, MGC82612 antibody, PARP11 antibody, RGD1561791 antibody, poly (ADP-ribose) polymerase family, member 11 antibody, poly(ADP-ribose) polymerase family member 11 antibody, poly(ADP-ribose) polymerase family member 11 S homeolog antibody, poly(ADP-ribose) polymerase family member 11 L homeolog antibody, Parp11 antibody, PARP11 antibody, parp11.S antibody, parp11.L antibody, parp11 antibody

Background: Poly(ADP-ribosylation) is a method of DNA damage-dependent posttranslational modification that helps to rescue injured proliferating cells from cell death. The PARP (poly(ADP-ribose) polymerase) proteins comprise a superfamily of enzymes that functionally modify histones and other nuclear proteins, thereby preventing cell death. PARPs use NAD+ as a substrate to catalytically transfer ADP-ribose residues onto protein acceptors, a process that, when repeated multiple times, leads to the formation of poly(ADPribose) chains on the protein.

UniProt: Q9NR21