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NEDD4-2 antibody

NEDD4L Reactivity: Human, Mouse ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7237525
  • Target See all NEDD4-2 (NEDD4L) Antibodies
    NEDD4-2 (NEDD4L) (E3 ubiquitin-protein ligase NEDD4-like (NEDD4L))
    Reactivity
    • 65
    • 43
    • 16
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 74
    • 4
    Rabbit
    Clonality
    • 69
    • 9
    Polyclonal
    Conjugate
    • 29
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NEDD4-2 antibody is un-conjugated
    Application
    • 36
    • 24
    • 13
    • 13
    • 7
    • 6
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant protein of human NEDD4L
    Isotype
    IgG
    Top Product
    Discover our top product NEDD4L Primary Antibody
  • Application Notes
    IHC 1:100-1:300
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.4 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    NEDD4-2 (NEDD4L) (E3 ubiquitin-protein ligase NEDD4-like (NEDD4L))
    Alternative Name
    NEDD4L (NEDD4L Products)
    Synonyms
    NEDD4-2 antibody, NEDD4.2 antibody, RSP5 antibody, hNEDD4-2 antibody, nedd4 antibody, nedd4-2 antibody, NEDD4 antibody, Nedd4-2 antibody, 1300012C07Rik antibody, Nedd4b antibody, neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase antibody, NEDD4L antibody, neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase S homeolog antibody, neural precursor cell expressed, developmentally down-regulated gene 4-like antibody, NEDD4L antibody, LOC776799 antibody, nedd4l.S antibody, Nedd4l antibody
    Background
    This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension.
    UniProt
    Q96PU5
    Pathways
    Negative Regulation of Transporter Activity
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