PARN antibody

Catalog No. ABIN7237468

Product Details anti-PARN Antibody

Target: PARN (Poly A Specific Ribonuclease (PARN))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PARN antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human NBL1

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PARN

Target: PARN (Poly A Specific Ribonuclease (PARN))

Alternative Name: DAN (PARN Products)

Synonyms: parn-A antibody, xparn antibody, DAN antibody, RGD1565449 antibody, zgc:56067 antibody, 1200003I18Rik antibody, poly(A)-specific ribonuclease L homeolog antibody, poly(A)-specific ribonuclease antibody, poly(A)-specific ribonuclease (deadenylation nuclease) antibody, parn.L antibody, PARN antibody, Parn antibody, parn antibody

Background: This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development.

NCBI Accession: NP_005371

UniProt: P41271