MAGEA10 antibody, CT1.10 antibody, MAGE10 antibody, RGD1563693 antibody, MAGEA11 antibody, MAGE family member A10 antibody, melanoma-associated antigen 10 antibody, melanoma antigen family A, 10 antibody, putative MAGE domain-containing protein MAGEA13P antibody, MAGEA10 antibody, LOC509805 antibody, Magea10 antibody, LOC492173 antibody
Background
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants.