HYAL3 antibody

Catalog No. ABIN7237226

Product Details anti-HYAL3 Antibody

Target: HYAL3 (Hyaluronidase-3 (HYAL3))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HYAL3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human HYAL3

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for HYAL3

Target: HYAL3 (Hyaluronidase-3 (HYAL3))

Alternative Name: HYAL3 (HYAL3 Products)

Synonyms: HYAL1 antibody, HYAL3 antibody, Hyal-3 antibody, HYAL-3 antibody, LUCA-3 antibody, LUCA3 antibody, Hyl3 antibody, hyaluronoglucosaminidase 3 antibody, HYAL3 antibody, Hyal3 antibody

Background: This gene encodes a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. The regulated turnover of hyaluronan plays a critical role in many biological processes including cell proliferation, migration and differentiation. The encoded protein may also play an important role in sperm function. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression, and the expression of specific transcript variants may be indicative of tumor status. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and some isoforms may lack hyaluronidase activity. This gene overlaps and is on the same strand as N-acetyltransferase 6 (GCN5-related), and some transcripts of each gene share a portion of the first exon.

Molecular Weight: 47 kDa

UniProt: O43820

Pathways: Glycosaminoglycan Metabolic Process