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FGFRL1 antibody

FGFRL1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7237000
  • Target See all FGFRL1 Antibodies
    FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))
    Reactivity
    • 51
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 52
    • 1
    • 1
    Rabbit
    Clonality
    • 52
    • 2
    Polyclonal
    Conjugate
    • 19
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FGFRL1 antibody is un-conjugated
    Application
    • 42
    • 21
    • 20
    • 13
    • 13
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant protein of human FGFRL1
    Isotype
    IgG
    Top Product
    Discover our top product FGFRL1 Primary Antibody
  • Application Notes
    WB 1:200-1:1000, IHC 1:100-1:300
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.6 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))
    Alternative Name
    FGFRL1 (FGFRL1 Products)
    Synonyms
    fgfrl1 antibody, zgc:64084 antibody, FGFR5 antibody, FGFR5beta antibody, FGFR5gamma antibody, Fgfr5 antibody, FHFR antibody, XFGFRL1 antibody, Xndk antibody, fgfrl1-a antibody, fgfrl1-b antibody, ndk antibody, im:7154242 antibody, fibroblast growth factor receptor like 1a antibody, fibroblast growth factor receptor-like 1 antibody, fibroblast growth factor receptor like 1 antibody, fibroblast growth factor receptor like 1 L homeolog antibody, fibroblast growth factor receptor like 1b antibody, fgfrl1a antibody, Fgfrl1 antibody, FGFRL1 antibody, fgfrl1.L antibody, fgfrl1b antibody
    Background
    The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene.
    Molecular Weight
    55 kDa
    NCBI Accession
    NP_068742
    UniProt
    Q8N441
    Pathways
    RTK Signaling
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