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Retinoblastoma Binding Protein 8 antibody

RBBP8 Reactivity: Human, Mouse, Rat ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7236693
  • Target See all Retinoblastoma Binding Protein 8 (RBBP8) Antibodies
    Retinoblastoma Binding Protein 8 (RBBP8)
    Reactivity
    • 51
    • 22
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 48
    • 3
    Rabbit
    Clonality
    • 48
    • 3
    Polyclonal
    Conjugate
    • 35
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Retinoblastoma Binding Protein 8 antibody is un-conjugated
    Application
    • 31
    • 20
    • 8
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant protein of human RBBP8
    Isotype
    IgG
    Top Product
    Discover our top product RBBP8 Primary Antibody
  • Application Notes
    IHC 1:100-1:300
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.7 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Retinoblastoma Binding Protein 8 (RBBP8)
    Alternative Name
    RBBP8 (RBBP8 Products)
    Background
    The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.
    UniProt
    Q99708
    Pathways
    Cell Division Cycle, DNA Damage Repair
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