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CRELD2 antibody

CRELD2 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7236677
  • Target See all CRELD2 Antibodies
    CRELD2 (Cysteine-Rich with EGF-Like Domains 2 (CRELD2))
    Reactivity
    • 43
    • 17
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 54
    • 4
    Rabbit
    Clonality
    • 57
    • 1
    Polyclonal
    Conjugate
    • 17
    • 6
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CRELD2 antibody is un-conjugated
    Application
    • 50
    • 30
    • 14
    • 13
    • 13
    • 3
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant protein of human CRELD2
    Isotype
    IgG
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.3 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CRELD2 (Cysteine-Rich with EGF-Like Domains 2 (CRELD2))
    Alternative Name
    CRELD2 (CRELD2 Products)
    Synonyms
    zgc:66383 antibody, CRELD2 antibody, 5730592L21Rik antibody, C85758 antibody, RGD1310614 antibody, cysteine-rich with EGF-like domains 2 antibody, cysteine rich with EGF like domains 2 antibody, creld2 antibody, CRELD2 antibody, Creld2 antibody
    Background
    The epidermal growth factor (EGF) repeat-containing proteins constitute an expanding family of proteins that are involved in several cellular activities, such as blood coagulation, fibrinolysis, cell adhesion and neural and vertebrate development. CRELD2 (cysteine-rich with EGF-like domains 2) is a 353 amino acid protein that is ubiquitously expressed and contains two FU domains and two EGF-like domains. Localized to the endoplasmic reticulum and secreted into the cell, CRELD2 interacts with AChR4, possibly regulating its transport. Human CRELD2 shares 69 % amino acid identity with its mouse counterpart, suggesting a conserved role between species. Multiple isoforms of CRELD2 exist due to alternative splicing events. The gene encoding CRELD2 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.
    Molecular Weight
    38 kDa
    UniProt
    Q6UXH1
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