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DOK4 antibody

DOK4 Reactivity: Human, Mouse IHC, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7236107
  • Target See all DOK4 Antibodies
    DOK4 (Docking Protein 4 (DOK4))
    Reactivity
    • 49
    • 16
    • 14
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 49
    Rabbit
    Clonality
    • 49
    Polyclonal
    Conjugate
    • 18
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DOK4 antibody is un-conjugated
    Application
    • 35
    • 16
    • 16
    • 13
    • 13
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    Immunohistochemistry (IHC), ELISA
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant protein of human DOK4
    Isotype
    IgG
    Top Product
    Discover our top product DOK4 Primary Antibody
  • Application Notes
    IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    DOK4 (Docking Protein 4 (DOK4))
    Alternative Name
    DOK4 (DOK4 Products)
    Synonyms
    DOK4 antibody, docking protein 4 antibody, DOK4 antibody, Dok4 antibody
    Background
    Docking protein 4is aproteinthat in humans is encoded by theDOK4gene. Dok-4 is a 326 amino acid protein that contains one PH domain and one IRS-type PTB domain and belongs to the Dok family of interacting proteins. Expressed in a variety of tissues with highest expression in liver, heart, kidney and skeletal muscle, Dok-4 plays an important role in Ret-mediated neurite outgrowth and may link Ret with downstream effectors during neuronal differentiation. Additionally, Dok-4 is thought to play a positive role in the activation of MAPK pathways and may participate in T-cell induced immune system regulation. Overexpression of Dok-4 is associated with clear cell renal cell carcinoma, suggesting a role for Dok-4 in tumorigenesis.
    UniProt
    Q8TEW6
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