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RICTOR antibody
RICTOR
Reactivity: Human, Mouse
IHC, ELISA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-RICTOR Antibody
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Target
See all RICTOR Antibodies
RICTOR
(RPTOR Independent Companion of mTOR, Complex 2 (RICTOR))
Reactivity
All reactivities for RICTOR antibodies
Human, Mouse
Host
All hosts for RICTOR antibodies
Rabbit
Clonality
All clonalities for RICTOR antibodies
Polyclonal
Conjugate
All conjugates for RICTOR antibodies
This RICTOR antibody is un-conjugated
Application
All applications for RICTOR antibodies
Immunohistochemistry (IHC), ELISA
Characteristics
Polyclonal Antibody
Purification
Affinity purification
Immunogen
Recombinant protein of human RICTOR
Isotype
IgG
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Discover our top product RICTOR Primary Antibody
Alternatives
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Application Details
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Application Notes
IHC 1:25-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.3 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for RICTOR
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Target
RICTOR
(RPTOR Independent Companion of mTOR, Complex 2 (RICTOR))
Alternative Name
RICTOR (RICTOR Products )
Synonyms
PIA antibody, mAVO3 antibody, 4921505C17Rik antibody, 6030405M08Rik antibody, AVO3 antibody, AW492497 antibody, D530039E11Rik antibody, Fyb antibody, RPTOR independent companion of MTOR complex 2 antibody, RPTOR independent companion of MTOR, complex 2 antibody, RICTOR antibody, Rictor antibody
Background
Rapamycin-insensitive companion of mTORis aproteinthat in humans is encoded by theRICTORgene. RICTOR and MTOR are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth. Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors.
UniProt
Q6R327
Pathways
Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Regulation of Actin Filament Polymerization , CXCR4-mediated Signaling Events
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