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EPS15L1 antibody
EPS15L1
Reactivity: Human, Mouse
WB, ELISA, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-EPS15L1 Antibody
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Target
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EPS15L1
(Epidermal Growth Factor Receptor Pathway Substrate 15-Like 1 (EPS15L1))
Reactivity
All reactivities for EPS15L1 antibodies
Human, Mouse
Host
All hosts for EPS15L1 antibodies
Rabbit
Clonality
All clonalities for EPS15L1 antibodies
Polyclonal
Conjugate
All conjugates for EPS15L1 antibodies
This EPS15L1 antibody is un-conjugated
Application
All applications for EPS15L1 antibodies
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
Characteristics
Polyclonal Antibody
Purification
Affinity purification
Immunogen
Recombinant protein of human EPS15L1
Isotype
IgG
Alternatives
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Application Details
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Application Notes
WB 1:500-1:2000, IHC 1:25-1:100
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.1 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for EPS15L1
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Target
EPS15L1
(Epidermal Growth Factor Receptor Pathway Substrate 15-Like 1 (EPS15L1))
Alternative Name
EPS15L1 (EPS15L1 Products )
Synonyms
Eps15R antibody, XEps15R antibody, EPS15R antibody, 9830147J04Rik antibody, AI593686 antibody, Eps15-rs antibody, epidermal growth factor receptor pathway substrate 15-like 1 S homeolog antibody, epidermal growth factor receptor pathway substrate 15 like 1 antibody, epidermal growth factor receptor pathway substrate 15-like 1 antibody, eps15l1.S antibody, EPS15L1 antibody, Eps15l1 antibody
Background
Epidermal growth factor receptor substrate 15-like 1is aproteinthat in humans is encoded by theEPS15L1gene. Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR), internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. Interacts with EPS15, AGFG1/HRB and AGFG2/HRBL. Associates with the clathrin-associated adapter protein complex 2 (AP-2) By similarity. Interacts with FCHO1. Interacts with FCHO2. Interacts (via EH domains) with DAB2.
Molecular Weight
94 kDa
UniProt
Q9UBC2
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