USP2 antibody

Catalog No. ABIN7236025

Product Details anti-USP2 Antibody

Target: USP2 (Ubiquitin Specific Peptidase 2 (USP2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human USP2

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for USP2

Target: USP2 (Ubiquitin Specific Peptidase 2 (USP2))

Alternative Name: USP2 (USP2 Products)

Synonyms: UBP41 antibody, USP9 antibody, B930035K21Rik antibody, Ubp41 antibody, UBP-t antibody, UBP46 antibody, ubp52 antibody, ubp66 antibody, zgc:92134 antibody, ubiquitin specific peptidase 2 antibody, ubiquitin specific peptidase 2a antibody, USP2 antibody, Usp2 antibody, usp2a antibody

Background: This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

UniProt: O75604