SETD2 antibody

Catalog No. ABIN7235965

Product Details anti-SETD2 Antibody

Target: SETD2 (SET Domain Containing 2 (SETD2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SETD2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human SETD2

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SETD2

Target: SETD2 (SET Domain Containing 2 (SETD2))

Alternative Name: SETD2 (SETD2 Products)

Synonyms: Kif9 antibody, HBP231 antibody, HIF-1 antibody, HIP-1 antibody, HYPB antibody, KMT3A antibody, SET2 antibody, p231HBP antibody, SET domain containing 2 antibody, Setd2 antibody, SETD2 antibody

Background: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.

UniProt: Q9BYW2

Pathways: Tube Formation