ARHGEF10 antibody

Catalog No. ABIN7235925

Product Details anti-ARHGEF10 Antibody

Target: ARHGEF10 (rho Guanine Nucleotide Exchange Factor (GEF) 10 (ARHGEF10))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGEF10 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human ARHGEF10

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ARHGEF10

Target: ARHGEF10 (rho Guanine Nucleotide Exchange Factor (GEF) 10 (ARHGEF10))

Alternative Name: ARHGEF10 (ARHGEF10 Products)

Synonyms: ARHGEF10 antibody, wu:fi38h08 antibody, GEF10 antibody, 6430549H08Rik antibody, mKIAA0294 antibody, Rho guanine nucleotide exchange factor 10 antibody, Rho guanine nucleotide exchange factor (GEF) 10 antibody, ARHGEF10 antibody, arhgef10 antibody, Arhgef10 antibody

Background: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. ARHGEF10 (rho guanine nucleotide exchange factor 10), also known as GEF10 or KIAA0294, is a 1,369 amino acid protein that contains one DBL-homology domain and is thought to play a role in myelination of peripheral nerves, specifically during development. ARHGEF10 is expressed as four alternatively spliced isoforms that are present at low levels in ovary, lung, testis and kidney, with considerably higher expression in the central and peripheral nervous systems.

UniProt: O15013