AMIGO2 antibody

Catalog No. ABIN7235835

Product Details anti-AMIGO2 Antibody

Target: AMIGO2 (Adhesion Molecule with Ig-Like Domain 2 (AMIGO2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AMIGO2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human AMIGO2

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for AMIGO2

Target: AMIGO2 (Adhesion Molecule with Ig-Like Domain 2 (AMIGO2))

Alternative Name: AMIGO2 (AMIGO2 Products)

Synonyms: AMIGO2 antibody, AI415330 antibody, AMIGO-2 antibody, AW208913 antibody, Ali1 antibody, ALI1 antibody, DEGA antibody, adhesion molecule with Ig like domain 2 antibody, adhesion molecule with Ig-like domain 2 antibody, AMIGO2 antibody, Amigo2 antibody

Background: The amphoterin-induced gene and ORF (AMIGO) family of proteins consists of AMIGO-1, AMIGO-2 and AMIGO-3. All three members are single pass type I membrane proteins that contain several leucine-rich repeats, one IgG domain, and a transmembrane domain. The AMIGO proteins are specifically expressed on fiber tracts of neuronal tissues and participate in their formation. The AMIGO proteins can form complexes with each other, but can also bind itself. AMIGO-1, also designated Alivin-2, promotes growth and fasciculation of neurites and plays a role in myelination and fasciculation of developing neural axons. In cerebellar neurons, AMIGO-2 (Alivin-1) is crucial for depolarization-dependent survival. Similar to AMIGO-1 and AMIGO-2, AMIGO-3 (Alivin-3) plays a role in homophilic and/or heterophilic cell-cell interaction and signal transduction

Molecular Weight: 58 kDa

UniProt: Q86SJ2