ACMSD antibody

Catalog No. ABIN7235726

Product Details anti-ACMSD Antibody

Target: ACMSD (Aminocarboxymuconate Semialdehyde Decarboxylase (ACMSD))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACMSD antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human ACMSD

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ACMSD

Target: ACMSD (Aminocarboxymuconate Semialdehyde Decarboxylase (ACMSD))

Alternative Name: ACMSD (ACMSD Products)

Synonyms: zgc:162888 antibody, ACMSD antibody, aminocarboxymuconate semialdehyde decarboxylase antibody, aminocarboxymuconate semialdehyde decarboxylase S homeolog antibody, amino carboxymuconate semialdehyde decarboxylase antibody, ACMSD antibody, acmsd antibody, acmsd.S antibody, Acmsd antibody

Background: The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase, EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.

Molecular Weight: 38 kDa

UniProt: Q8TDX5