ABC27 antibody, ABC50 antibody, AU041969 antibody, Abc50 antibody, D17Wsu166e antibody, GCN20 antibody, zgc:85667 antibody, wu:fb79c06 antibody, wu:fc39a05 antibody, wu:fj94a08 antibody, ABCF1 antibody, MGC81714 antibody, ATP binding cassette subfamily F member 1 antibody, ATP-binding cassette, sub-family F (GCN20), member 1 antibody, ATP binding cassette subfamily F member 1 L homeolog antibody, ATP-binding cassette sub-family F member 1 antibody, ABCF1 antibody, Abcf1 antibody, abcf1 antibody, abcf1.L antibody, CpipJ_CPIJ005705 antibody, TGME49_318710 antibody, PITG_06772 antibody
Background
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the GCN20 subfamily. Unlike other members of the superfamily, this protein lacks the transmembrane domains which are characteristic of most ABC transporters. This protein may be regulated by tumor necrosis factor-alpha and play a role in enhancement of protein synthesis and the inflammation process.