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Synaptotagmin 3 antibody

SYT3 Reactivity: Human, Mouse, Rat ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7235576
  • Target See all Synaptotagmin 3 (SYT3) Antibodies
    Synaptotagmin 3 (SYT3) (Synaptotagmin III (SYT3))
    Reactivity
    • 21
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 20
    • 1
    • 1
    Rabbit
    Clonality
    • 21
    • 1
    Polyclonal
    Conjugate
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Synaptotagmin 3 antibody is un-conjugated
    Application
    • 8
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant protein of human SYT3
    Isotype
    IgG
  • Application Notes
    IHC 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Synaptotagmin 3 (SYT3) (Synaptotagmin III (SYT3))
    Alternative Name
    SYT3 (SYT3 Products)
    Synonyms
    SytIII antibody, AI385753 antibody, sytIII antibody, SIII antibody, synaptotagmin 3 antibody, synaptotagmin III antibody, SYT3 antibody, Syt3 antibody
    Background
    Synaptotagmins are a large gene family of synaptic vesicle type III integral membrane proteins that function as regulators of both exocytosis and endocytosis and are involved in neurotransmitter secretion from small secretory vesicles. Calcium binds to Synaptotagmin I which triggers neurotransmitter release at the synapse. Synaptotagmin II is phosphorylated by WNK1 in a process that regulates calcium-dependent interactions. Synaptotagmin III is involved in calcium-dependent exocytosis of secretory vesicles in endocrine cells and neurons. Synaptotagmin IV is expressed in neuronal tissues, and has the highest mRNA levels in the hippocampus. The proximity of the Synaptotagmin IV gene to markers of several psychiatric disorders suggest an involvement of synaptotagmin IV in human disease. Synaptotagmin V is a dense-core vesicle-specific protein that regulates a specific type of calcium-regulated secretion. Synaptotagmin VI interacts with adaptor protein-2 in a calcium-independent manner. Synaptotagmin VII is widely expressed in non-neuronal tissues.
    UniProt
    Q9BQG1
    Pathways
    Synaptic Vesicle Exocytosis
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