SLC4A4 antibody

Catalog No. ABIN7235532

Product Details anti-SLC4A4 Antibody

Target: SLC4A4 (Solute Carrier Family 4, Sodium Bicarbonate Cotransporter, Member 4 (SLC4A4))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC4A4 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human SLC4A4

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SLC4A4

Target: SLC4A4 (Solute Carrier Family 4, Sodium Bicarbonate Cotransporter, Member 4 (SLC4A4))

Alternative Name: SLC4A4 (SLC4A4 Products)

Synonyms: HNBC1 antibody, KNBC antibody, NBC1 antibody, NBC2 antibody, NBCe1-A antibody, SLC4A5 antibody, hhNMC antibody, pNBC antibody, NBCE1 antibody, AI835705 antibody, NBC antibody, HHNMC antibody, Nbc1 antibody, Nbc4 antibody, PNBC antibody, id:ibd2520 antibody, nbce1 antibody, si:dkey-256m11.1 antibody, slc4a4 antibody, solute carrier family 4 member 4 antibody, solute carrier family 4 (anion exchanger), member 4 antibody, solute carrier family 4 (sodium bicarbonate cotransporter), member 4a antibody, SLC4A4 antibody, Slc4a4 antibody, slc4a4a antibody

Background: This gene encodes a sodium bicarbonate cotransporter (NBC) involved in the regulation of bicarbonate secretion and absorption and intracellular pH . Mutations in this gene are associated with proximal renal tubular acidosis. Multiple transcript variants encoding different isoforms have been found for this gene. Sodium bicarbonate cotransporters (NBCs) mediate the coupled movement of sodium and bicarbonate ions across the plasma membrane of many cells. This is an electrogenic process with an apparent stoichiometry of 3 bicarbonate ions per sodium ion. Sodium bicarbonate cotransport is involved in bicarbonate secretion/absorption and intracellular pH regulation. Romero and Boron (1999) reviewed NBCs. Soleimani and Burnham (2000) reviewed NBCs and their regulation in physiologic and pathophysiologic states.

UniProt: Q9Y6R1