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MLH1 antibody
MLH1
Reactivity: Human, Mouse, Rat
ELISA, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MLH1 Antibody
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Target
See all MLH1 Antibodies
MLH1
(MutL Homolog 1 (MLH1))
Reactivity
All reactivities for MLH1 antibodies
Human, Mouse, Rat
Host
All hosts for MLH1 antibodies
Rabbit
Clonality
All clonalities for MLH1 antibodies
Polyclonal
Conjugate
All conjugates for MLH1 antibodies
This MLH1 antibody is un-conjugated
Application
All applications for MLH1 antibodies
ELISA, Immunohistochemistry (IHC)
Characteristics
Polyclonal Antibody
Purification
Affinity purification
Immunogen
Recombinant protein of human MLH1
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
IHC 1:50-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.8 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for MLH1
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Target
MLH1
(MutL Homolog 1 (MLH1))
Alternative Name
MLH1 (MLH1 Products )
Synonyms
CG11482 antibody, Dmel\\CG11482 antibody, dmlh-1 antibody, dmlh1 antibody, zgc:66301 antibody, MLH1 antibody, LOC100232198 antibody, 1110035C23Rik antibody, AI317206 antibody, AI325952 antibody, AI561766 antibody, COCA2 antibody, FCC2 antibody, HNPCC antibody, HNPCC2 antibody, hMLH1 antibody, mutL homolog 1 antibody, CG11482 gene product from transcript CG11482-RB antibody, mutL homolog 1 S homeolog antibody, mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) antibody, DNA mismatch repair protein Mlh1 antibody, MLH1 antibody, Mlh1 antibody, mlh1.S antibody, mlh1 antibody, LOC588545 antibody
Background
This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.
UniProt
P40692
Pathways
DNA Damage Repair , Production of Molecular Mediator of Immune Response
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