ELAV1 antibody, HUR antibody, Hua antibody, MelG antibody, HuR antibody, 2410055N02Rik antibody, W91709 antibody, elra antibody, fa25f08 antibody, fb59a02 antibody, fc60g02 antibody, hua antibody, wu:fa25f08 antibody, wu:fb59a02 antibody, wu:fc60g02 antibody, zHuA antibody, Elavl1 antibody, Xel-1 antibody, elav1 antibody, elrA antibody, hur antibody, melg antibody, p36 antibody, ElrA antibody, elavl1 antibody, elavl1-a antibody, elavl1-b antibody, ELAV like RNA binding protein 1 antibody, ELAV-like protein 1 antibody, ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R) antibody, ELAV like RNA binding protein 1a antibody, ELAV like RNA binding protein 1 L homeolog antibody, ELAV like RNA binding protein 1 S homeolog antibody, ELAVL1 antibody, Elavl1 antibody, elav1 antibody, elavl1a antibody, elavl1.L antibody, elavl1.S antibody
Background
The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy.