AARS2 antibody

Catalog No. ABIN7234729

Product Details anti-AARS2 Antibody

Target: AARS2 (Alanyl-tRNA Synthetase 2, Mitochondrial (AARS2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AARS2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human AARS2

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for AARS2

Target: AARS2 (Alanyl-tRNA Synthetase 2, Mitochondrial (AARS2))

Alternative Name: AARS2 (AARS2 Products)

Synonyms: AARSL antibody, COXPD8 antibody, MT-ALARS antibody, MTALARS antibody, Aarsl antibody, AlaRS antibody, Gm89 antibody, alanyl-tRNA synthetase 2, mitochondrial antibody, AARS2 antibody, Aars2 antibody

Background: The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8. Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain

Molecular Weight: 107 kDa

UniProt: Q5JTZ9