MPS-1 antibody, MPS1 antibody, S27 antibody, 3200001M24Rik antibody, GB13072 antibody, DDBDRAFT_0203425 antibody, DDBDRAFT_0231065 antibody, DDB_0203425 antibody, DDB_0231065 antibody, mps-1 antibody, mps1 antibody, ribosomal protein S27 antibody, 40S ribosomal protein S27 antibody, ribosomal protein S27 pseudogene antibody, Ribosomal protein S27, component of cytosolic 80S ribosome and 40S small subunit antibody, component of 80S ribosome and 40S small subunit antibody, ribosomal protein S27 L homeolog antibody, RPS27 antibody, Rps27 antibody, LOC726295 antibody, RPS27P antibody, rps27 antibody, rps27.L antibody, rps-27 antibody
Background
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S27E family of ribosomal proteins. It contains a C4-type zinc finger domain that can bind to zinc. The encoded protein has been shown to be able to bind to nucleic acid. It is located in the cytoplasm as a ribosomal component, but it has also been detected in the nucleus. Studies in rat indicate that ribosomal protein S27 is located near ribosomal protein S18 in the 40S subunit and is covalently linked to translation initiation factor eIF3. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.