Fibrinogen beta Chain antibody

Catalog No. ABIN7234414

Product Details anti-Fibrinogen beta Chain Antibody

Target: Fibrinogen beta Chain (FGB)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fibrinogen beta Chain antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen Affinity Purification

Immunogen: Recombinant Human Fibrinogen beta chain protein

Isotype: IgG

Application Details

Application Notes: WB 1:2000-1:4000 IHC 1:100-1:300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.05 % Proclin300, 50 % glycerol, pH 7.3

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Fibrinogen beta Chain

Target: Fibrinogen beta Chain (FGB)

Alternative Name: FGB (FGB Products)

Synonyms: FGB antibody, 2510049G14Rik antibody, DKFZp470D0312 antibody, LOC100223598 antibody, fibrinogen antibody, Ab1-216 antibody, Ac1-581 antibody, wu:fa55c11 antibody, zgc:77116 antibody, fgb antibody, fibrinogen beta chain antibody, fibrinogen beta chain L homeolog antibody, FGB antibody, Fgb antibody, fgb antibody, fgb.L antibody

Background: The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.

Molecular Weight:

Observed_MW: 55 kDa

Calculated_MW: 55 kDa

Gene ID: 2244

UniProt: P02675