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MCAM antibody

MCAM Reactivity: Human, Mouse, Rat IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6999958
  • Target See all MCAM Antibodies
    MCAM (Melanoma Cell Adhesion Molecule (MCAM))
    Reactivity
    • 124
    • 46
    • 45
    • 14
    • 14
    • 9
    • 8
    • 7
    • 6
    • 2
    Human, Mouse, Rat
    Host
    • 95
    • 53
    • 1
    • 1
    • 1
    Rabbit
    Clonality
    • 88
    • 63
    Polyclonal
    Conjugate
    • 70
    • 14
    • 12
    • 9
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MCAM antibody is un-conjugated
    Application
    • 84
    • 67
    • 66
    • 43
    • 18
    • 18
    • 14
    • 10
    • 10
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB)
    Characteristics
    Polyclonal Antibody
    Purification
    Antigen Affinity Purification
    Immunogen
    Recombinant Human Cell surface glycoprotein MUC18 protein
    Isotype
    IgG
    Top Product
    Discover our top product MCAM Primary Antibody
  • Application Notes
    WB 1:500-1:1000 IHC 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.48 mg/mL
    Buffer
    PBS with 0.05 % Proclin300, 50 % glycerol, pH 7.3
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MCAM (Melanoma Cell Adhesion Molecule (MCAM))
    Alternative Name
    CD146 (MCAM Products)
    Synonyms
    CD146 antibody, MUC18 antibody, Muc18 antibody, 1-gicerin antibody, AV025631 antibody, CD149 antibody, s-endo antibody, s-gicerin antibody, cd146 antibody, gicerin antibody, id:ibd3512 antibody, mcam antibody, MCAM antibody, melanoma cell adhesion molecule antibody, melanoma cell adhesion molecule b antibody, MCAM antibody, Mcam antibody, mcamb antibody
    Background
    CD146,also known as melanoma cell adhesion molecule (MCAM) or MUC18,originally identified as a biomarker of melanoma progression,is a transmembrane glycoprotein belonging to the immunoglobulin (Ig) superfamily . Structurally,it consists of five Ig domains,a transmembrane domain,and a cytoplasmic region. In normal adult tissue,CD146 is primarily expressed by vascular endothelium and smooth muscle. CD146 is a key cell adhesion protein in vascular endothelial cell activity and angiogenesis,and has been used as marker of circulating endothelium cells (CECs) .
    Molecular Weight

    Observed_MW: 57,71 kDa

    Calculated_MW: 57,71 kDa

    Gene ID
    4162
    UniProt
    P43121
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