MCAM antibody
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- Target See all MCAM Antibodies
- MCAM (Melanoma Cell Adhesion Molecule (MCAM))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MCAM antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), Western Blotting (WB)
- Characteristics
- Polyclonal Antibody
- Purification
- Antigen Affinity Purification
- Immunogen
- Recombinant Human Cell surface glycoprotein MUC18 protein
- Isotype
- IgG
- Top Product
- Discover our top product MCAM Primary Antibody
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- Application Notes
- WB 1:500-1:1000 IHC 1:50-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.48 mg/mL
- Buffer
- PBS with 0.05 % Proclin300, 50 % glycerol, pH 7.3
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- MCAM (Melanoma Cell Adhesion Molecule (MCAM))
- Alternative Name
- CD146 (MCAM Products)
- Synonyms
- CD146 antibody, MUC18 antibody, Muc18 antibody, 1-gicerin antibody, AV025631 antibody, CD149 antibody, s-endo antibody, s-gicerin antibody, cd146 antibody, gicerin antibody, id:ibd3512 antibody, mcam antibody, MCAM antibody, melanoma cell adhesion molecule antibody, melanoma cell adhesion molecule b antibody, MCAM antibody, Mcam antibody, mcamb antibody
- Background
- CD146,also known as melanoma cell adhesion molecule (MCAM) or MUC18,originally identified as a biomarker of melanoma progression,is a transmembrane glycoprotein belonging to the immunoglobulin (Ig) superfamily . Structurally,it consists of five Ig domains,a transmembrane domain,and a cytoplasmic region. In normal adult tissue,CD146 is primarily expressed by vascular endothelium and smooth muscle. CD146 is a key cell adhesion protein in vascular endothelial cell activity and angiogenesis,and has been used as marker of circulating endothelium cells (CECs) .
- Molecular Weight
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Observed_MW: 57,71 kDa
Calculated_MW: 57,71 kDa
- Gene ID
- 4162
- UniProt
- P43121
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