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KNSTRN antibody

KNSTRN Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7233849
  • Target See all KNSTRN Antibodies
    KNSTRN (Kinetochore-Localized Astrin/SPAG5 Binding Protein (KNSTRN))
    Reactivity
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 5
    Rabbit
    Clonality
    • 5
    Polyclonal
    Conjugate
    • 5
    This KNSTRN antibody is un-conjugated
    Application
    • 4
    • 1
    • 1
    Western Blotting (WB)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant Human Small kinetochore-associated protein protein
    Isotype
    IgG
  • Application Notes
    WB 1:500-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    2 mg/mL
    Buffer
    PBS with 0.05 % Proclin300 and 50 % glycerol, pH 7.4.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    KNSTRN (Kinetochore-Localized Astrin/SPAG5 Binding Protein (KNSTRN))
    Alternative Name
    C15orf23 (KNSTRN Products)
    Synonyms
    1700025D04Rik antibody, C15orf23 antibody, D2Ertd750e antibody, SKAP antibody, Traf4af1 antibody, TRAF4AF1 antibody, kinetochore-localized astrin/SPAG5 binding antibody, kinetochore localized astrin/SPAG5 binding protein antibody, kinetochore-localized astrin/SPAG5 binding protein antibody, Knstrn antibody, KNSTRN antibody
    Background
    Essential component of the mitotic spindle required for faithful chromosome segregation and progression into anaphase . Promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments. Required for kinetochore oscillations and dynamics of microtubule plus-ends during live cell mitosis, possibly by forming a link between spindle microtubule plus-ends and mitotic chromosomes to achieve faithful cell division.
    Molecular Weight

    Observed_MW: 35 kDa

    Calculated_MW: 35 kDa

    UniProt
    Q9Y448
    Pathways
    M Phase
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