Integrin beta 3 antibody (AA 134-376)

Catalog No. ABIN7439249

Product Details anti-Integrin beta 3 Antibody

Target: Integrin beta 3 (ITGB3)

Binding Specificity: AA 134-376

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Integrin beta 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Purpose: Polyclonal Antibody to Integrin Beta 3 (ITGb3)

Specificity: The antibody is a rabbit polyclonal antibody raised against ITGb3. It has been selected for its ability to recognize ITGb3 in immunohistochemical staining and western blotting.

Cross-Reactivity: Human, Rat

Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: Recombinant Integrin Beta 3 (ITGb3) corresdonding to Asp134~Ile376 with N-terminal His Tag

Isotype: IgG

Application Details

Application Notes:

Western blotting: 0.5-2 μg/mL

1:430-1700 Immunohistochemistry: 5-20 μg/mL

1:43-170 Immunocytochemistry: 5-20 μg/mL

1:43-170 Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, containing 0.02 % Sodium azide, 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Expiry Date: 24 months

Target Details for Integrin beta 3

Target: Integrin beta 3 (ITGB3)

Alternative Name: Integrin Beta 3 (ITGB3 Products)

Background: CD61, ITG-B3, GP3A, GP3-A, GpIIIa, Platelet Membrane Glycoprotein IIIa

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex