Cathepsin L antibody (AA 114-288)

Catalog No. ABIN7431587

Product Details anti-Cathepsin L Antibody

Target: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Binding Specificity: AA 114-288

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cathepsin L antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Purpose: Polyclonal Antibody to Cathepsin L (CTSL)

Specificity: The antibody is a rabbit polyclonal antibody raised against CTSL. It has been selected for its ability to recognize CTSL in immunohistochemical staining and western blotting.

Cross-Reactivity: Mouse

Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: Recombinant Cathepsin L (CTSL) corresdonding to Ile114~Thr288 with N-terminal His Tag

Isotype: IgG

Application Details

Application Notes:

Western blotting: 0.5-2 μg/mL

1:450-1800 Immunohistochemistry: 5-20 μg/mL

1:45-180 Immunocytochemistry: 5-20 μg/mL

1:45-180 Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, containing 0.02 % Sodium azide, 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Expiry Date: 24 months

References for anti-Cathepsin L antibody (ABIN7431587)

Zhang, Wei, Li, He, Liu, Deng, Cheng, Du, Liu, Chen, Sun, Yu, Fu: "COVID-19 receptor and malignant cancers: Association of CTSL expression with susceptibility to SARS-CoV-2." in: International journal of biological sciences, Vol. 18, Issue 6, pp. 2362-2371, (2022) (PubMed).

Target Details for Cathepsin L

Target: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Alternative Name: Cathepsin L (CTSL1 Products)

Background: CTSL1, CATL, CTS-L, MEP, Cathepsin L1, Major excreted protein

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades