SUSD3 antibody (AA 120-170)

Catalog No. ABIN6992182

Product Details anti-SUSD3 Antibody

Target: SUSD3 (Sushi Domain Containing 3 (SUSD3))

Binding Specificity: AA 120-170

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUSD3 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunocytochemistry (ICC)

Specificity: SUSD3 antibody is human and mouse reactive. Multiple isoforms of SUSD3 are known to exist.

Purification: SUSD3 Antibody is affinity chromatography purified via peptide column.

Immunogen: SUSD3 antibody was raised against a 16 amino acid peptide from near the center of human SUSD3. The immunogen is located within amino acids 120 - 170 of SUSD3.

Isotype: IgG

Application Details

Application Notes: SUSD3 antibody can be used for the detection of SUSD3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunocytochemistry in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: SUSD3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: SUSD3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for SUSD3

Target: SUSD3 (Sushi Domain Containing 3 (SUSD3))

Alternative Name: SUSD3 (SUSD3 Products)

Synonyms: 1700017I11Rik antibody, 2810440J20Rik antibody, sushi domain containing 3 antibody, SUSD3 antibody, Susd3 antibody

Background: Little is known of the function of the sushi domain containing 3 protein (SUSD3), but its expression has been reported in estrogen receptor-alpha (ERalpha)-positive breast tumors with decreased expression reported in aggressive malignant tumors (1,2). Recently, SUSD3 has been found to promote estrogen-dependent cell proliferation and may regulate cell-cell and cell-substrate interactions and migration in breast cancer (3). Furthermore, elevated SUSD3 mRNA levels were observed in aromatase inhibitor-responsive breast tumors, suggesting that it may also serve as a novel predictor of response to endocrine therapy and a potential therapeutic target (3).

Molecular Weight: Predicted: 16, 22, 23, 28 kDa

Observed: 23 kDa

Gene ID: 203328

NCBI Accession: NP_659443

UniProt: Q96L08