CHAD antibody (C-Term)

Catalog No. ABIN6992175

Product Details anti-CHAD Antibody

Target: CHAD (Chondroadherin (CHAD))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHAD antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunocytochemistry (ICC)

Specificity: Chondroadherin antibody is human and mouse reactive. Chondroadherin antibody is predicted to not cross-react with CHADL protein.

Purification: Chondroadherin antibody is affinity chromatography purified via peptide column.

Immunogen: Chondroadherin antibody was raised against a 17 amino acid peptide near the carboxy terminus of human Chondroadherin. The immunogen is located within the last 50 amino acids of Chondroadherin.

Isotype: IgG

Application Details

Application Notes: Chondroadherin antibody can be used for detection of Chondroadherin by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in mouse samples and Immunocytochemistry in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Chondroadherin antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: Chondroadherin antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for CHAD

Target: CHAD (Chondroadherin (CHAD))

Alternative Name: Chondroadherin (CHAD Products)

Synonyms: CHAD antibody, zgc:63475 antibody, SLRR4A antibody, chondroadherin antibody, CHAD antibody, chad antibody, Chad antibody

Background: Chondroadherin, also known as CHAD or SLRR4A, belongs to the small leucine-rich proteoglycan (SLRP) family and class IV subfamily and plays a significant role in the regulation of chondrocyte growth and proliferation (1,2). It localizes to the extracellular matrix and contains nine tandem leucine repeats as well as N-terminal and C-terminal leucine rich domains (2-4). Chondroadherin is implicated in the adhesion of fibroblasts, osteoblasts and chondrocytes, which is mediated by interactions with Integrin alpha2 beta1 (2,4,5).

Molecular Weight: Predicted: 38 kDa

Observed: 36 kDa

Gene ID: 1101

NCBI Accession: NP_001258

UniProt: O15335