VTI1A antibody (AA 50-100)

Catalog No. ABIN6992162

Product Details anti-VTI1A Antibody

Target: VTI1A (Vesicle Transport through Interaction with t-SNAREs 1A (VTI1A))

Binding Specificity: AA 50-100

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VTI1A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: VTI1a antibody is human, mouse and rat reactive. At least two isoforms of VTI1a are known to exist, this antibody will detect both isoforms. VTI1a antibody is predicted to not cross-react with VTI1b.

Purification: VTI1a antibody is affinity chromatography purified via peptide column.

Immunogen: VTI1a antibody was raised against a 19 amino acid peptide near the center of human VTI1a. The immunogen is located within amino acids 50 - 100 of VTI1a.

Isotype: IgG

Application Details

Application Notes: VTI1a antibody can be used for detection of VTI1a by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: VTI1a antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: VTI1a antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for VTI1A

Target: VTI1A (Vesicle Transport through Interaction with t-SNAREs 1A (VTI1A))

Alternative Name: VTI1a (VTI1A Products)

Background: Vesicle transport through interaction with t-SNAREs homolog 1 (VTI1a and VTI1b) are involved in vesicular transport from the late endosomes to the trans-Golgi network (1). They are both localized in the trans-Golgi network, with VTI1a also found in the Golgi apparatus and VTI1b in endosomes (2,3). VTI1a mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane and promotes fusion of the lipid bilayers (4). VTI1a may be concerned with increased secretion of cytokines associated with cellular senescence (5).

Molecular Weight: Predicted: 24, 27 kDa

Observed: 26 kDa

Gene ID: 143187

NCBI Accession: NP_660207

UniProt: Q96AJ9