TRO antibody (N-Term)

Catalog No. ABIN6992157

Product Details anti-TRO Antibody

Target: TRO (Trophinin (TRO))

Binding Specificity: AA 390-440, N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRO antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Trophinin antibody is human, mouse and rat reactive. Multiple isoforms of Trophinin are known to exist.

Purification: Trophinin antibody is affinity chromatography purified via peptide column.

Immunogen: Trophinin antibody was raised against a 16 amino acid peptide near the amino terminus of human Trophinin. The immunogen is located within amino acids 390 - 440 of Trophinin.

Isotype: IgG

Application Details

Application Notes: Trophinin antibody can be used for detection of Trophinin by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry at 10 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Trophinin antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: Trophinin antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for TRO

Target: TRO (Trophinin (TRO))

Alternative Name: Trophinin (TRO Products)

Synonyms: MAGE-d3 antibody, MAGED3 antibody, AA409408 antibody, Maged3 antibody, Maged3l antibody, Tnn antibody, Trol antibody, magphinin antibody, trophinin antibody, TRO antibody, Tro antibody

Background: Trophinin, also known as TRO or MAGED3, is an apical cell adhesion molecule that is implicated in the initial attachment during the process of embryo implantation and functions by mediating cell adhesion between trophoblastic and endometrial epithelial cells (1,2). Trophinin is a membrane protein expressed in chorionic villi trophoblasts and in maternal endometrial epithelial cells in an implantation-dependent manner and interacts with Bystin and Tastin, facilitating cell adhesion and embryo implantation (3,4). The induction of Trophinin expression may be a useful method for improving implantation rates and can be a potential diagnostic factor and biomarker for human cancer (4,5).

Molecular Weight: Predicted: 78, 157 kDa

Observed: 94 kDa

Gene ID: 7216

NCBI Accession: NP_001034794

UniProt: Q12816