Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificity
PALMD antibody is human specific. At least two isoforms are known to exist.
Purification
PALMD antibody is affinity chromatography purified via peptide column.
Immunogen
PALMD antibody was raised against a 15 amino acid peptide near the carboxy terminus of human PALMD. The immunogen is located within amino acids 460 - 510 of PALMD.
PALMD
Reactivity: Human
WB, IHC, ELISA
Host: Rabbit
Polyclonal
unconjugated
Application Notes
PALMD antibody can be used for detection of PALMD by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
PALMD antibody is supplied in PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C,4 °C
Storage Comment
PALMD antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Palmdelphin (PALMD) is a member of the paralemmin families that are lipid-anchored proteins having a role in the cell shape control and cell dynamics (1,2). While Paralemmin proteins typically anchor to the cytoplasm through via palmytoylation and prenylation, PALMD is found predominantly in the cytosol (3). PALMD is targeted to the nucleus to induce apoptosis in response to DNA damage (3-5). Abnormal genetic alterations in PALMD are observed in many malignant tumors (5).