Relaxin 3 antibody (AA 80-130)

Catalog No. ABIN6992136

Product Details anti-Relaxin 3 Antibody

Target: Relaxin 3 (RLN3)

Binding Specificity: AA 80-130

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Relaxin 3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: RLN3 antibody is human specific. RLN3 antibody is predicted to not cross-react with other members of the Relaxin protein family.

Purification: RLN3 antibody is affinity chromatography purified via peptide column.

Immunogen: RLN3 antibody was raised against a 19 amino acid peptide near the center of human RLN3. The immunogen is located within amino acids 80 - 130 of RLN3.

Isotype: IgG

Application Details

Application Notes: RLN3 antibody can be used for detection of RLN3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: RLN3 antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: RLN3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for Relaxin 3

Target: Relaxin 3 (RLN3)

Alternative Name: RLN3 (RLN3 Products)

Background: Relaxin-3 (RLN3) is a member of Relaxin family, a group of endocrine and autocrine/paracrine hormones that belong to the insulin gene superfamily (1,2). RLN3 can bind to and activate three relaxin-family peptide receptors: RXFP1, RXFP3, and RXFP4 (3). In contrast to the widespread expression of the related proteins RLN1 and RLN2, RLN3 is predominantly expressed in brain and to a lesser extent in the thymus, kidney and spleen (1). RLN3 has been suggested to play a role in feeding, metabolism, stress, arousal, learning, and memory (4).

Molecular Weight: Predicted: 16 kDa

Observed: 16 kDa

Gene ID: 117579

NCBI Accession: NP_543140

UniProt: Q8WFX3

Pathways: Hormone Activity, cAMP Metabolic Process