Relaxin 3 antibody (AA 80-130)

Catalog No. ABIN6992136

Product Details anti-Relaxin 3 Antibody

Target: Relaxin 3 (RLN3)

Binding Specificity: AA 80-130

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Relaxin 3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: RLN3 antibody is human specific. RLN3 antibody is predicted to not cross-react with other members of the Relaxin protein family.

Purification: RLN3 antibody is affinity chromatography purified via peptide column.

Immunogen: RLN3 antibody was raised against a 19 amino acid peptide near the center of human RLN3. The immunogen is located within amino acids 80 - 130 of RLN3.

Isotype: IgG

Application Details

Application Notes: RLN3 antibody can be used for detection of RLN3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: RLN3 antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: RLN3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for Relaxin 3

Target: Relaxin 3 (RLN3)

Alternative Name: RLN3 (RLN3 Products)

Synonyms: RFLB antibody, RLX3 antibody, RFLC2 antibody, rln3 antibody, rlx 3a antibody, rlx3a antibody, rxn3 antibody, RFLCI antibody, insl7 antibody, zins4 antibody, H3 antibody, RXN3 antibody, ZINS4 antibody, M3 antibody, Insl7 antibody, Relaxin-3 antibody, relaxin 3 antibody, relaxin 3a antibody, RLN3 antibody, rln3a antibody, rln3 antibody, Rln3 antibody

Background: Relaxin-3 (RLN3) is a member of Relaxin family, a group of endocrine and autocrine/paracrine hormones that belong to the insulin gene superfamily (1,2). RLN3 can bind to and activate three relaxin-family peptide receptors: RXFP1, RXFP3, and RXFP4 (3). In contrast to the widespread expression of the related proteins RLN1 and RLN2, RLN3 is predominantly expressed in brain and to a lesser extent in the thymus, kidney and spleen (1). RLN3 has been suggested to play a role in feeding, metabolism, stress, arousal, learning, and memory (4).

Molecular Weight: Predicted: 16 kDa

Observed: 16 kDa

Gene ID: 117579

NCBI Accession: NP_543140

UniProt: Q8WFX3

Pathways: Hormone Activity, cAMP Metabolic Process