R-Spondin 3 antibody (C-Term)

Catalog No. ABIN6992127

Product Details anti-R-Spondin 3 Antibody

Target: R-Spondin 3 (RSPO3)

Binding Specificity: AA 200-250, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This R-Spondin 3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: RSPO3 antibody is human and mouse reactive. At least three isoforms of RSPO3 are known to exist, this antibody will detect all three.

Purification: RSPO3 antibody is affinity chromatography purified via peptide column.

Immunogen: RSPO3 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human RSPO3. The immunogen is located within amino acids 200 - 250 of RSPO3.

Isotype: IgG

Application Details

Application Notes: RSPO3 antibody can be used for detection of RSPO3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: RSPO3 antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: RSPO3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for R-Spondin 3

Target: R-Spondin 3 (RSPO3)

Alternative Name: RSPO3 (RSPO3 Products)

Synonyms: pwtsr antibody, thsd2 antibody, cristin1 antibody, CRISTIN1 antibody, PWTSR antibody, THSD2 antibody, RGD1563246 antibody, 2810459H04Rik antibody, AW742308 antibody, Cristin1 antibody, Thsd2 antibody, R-spondin 3 antibody, rspo3 antibody, RSPO3 antibody, Rspo3 antibody

Background: RSPO3 is a member of the R-spondin family and plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis (1,2). RSPO3 has been shown to be involved in regulating the balance between angioblast and blood cell specification during embryonic vasculogenesis and angiogenesis and may be involved in tumor development (3,4).

Molecular Weight: Predicted: 30 kDa

Observed: 30 kDa

Gene ID: 84870

NCBI Accession: NP_116173

UniProt: Q9BXY4