ODZ1/Teneurin 1 antibody (N-Term)

Catalog No. ABIN6992125

Product Details anti-ODZ1/Teneurin 1 Antibody

Target: ODZ1/Teneurin 1 (TENM1) (Teneurin Transmembrane Protein 1 (TENM1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ODZ1/Teneurin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: TENM1 antibody is human, mouse and rat reactive. TENM1 antibody is predicted to not cross-react with other members of the TENM family.

Purification: TENM1 antibody is affinity chromatography purified via peptide column.

Immunogen: TENM1 antibody was raised against an 18 amino acid peptide near the amino terminus of human TENM1. The immunogen is located within the first 50 amino acids of TENM1.

Isotype: IgG

Application Details

Application Notes: TENM1 antibody can be used for detection of TENM1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: TENM1 antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: TENM1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for ODZ1/Teneurin 1

Target: ODZ1/Teneurin 1 (TENM1) (Teneurin Transmembrane Protein 1 (TENM1))

Alternative Name: TENM1 (TENM1 Products)

Synonyms: TEN-1 antibody, TENM1 antibody, ODZ1 antibody, ODZ3 antibody, TEN-M1 antibody, TNM antibody, TNM1 antibody, Odz1 antibody, Odz2 antibody, TCAP-1 antibody, Ten-m1 antibody, teneurin transmembrane protein 1 antibody, TENM1 antibody, Tenm1 antibody

Background: The teneurin transmembrane protein 1 (TENM1) is a member of a family of four neuronal cell surface proteins homologous to the Drosophila pair-rule gene Ten-m (1,2). TENM1 is expressed primarily in the developing central nervous system and may be proteolytically cleaved with the intracellular domain translocating to the nucleus (3). TENM1 is a direct target of the homeobox transcription factor EMX2, a transcription factor thought to be important for area specification in the developing cortex (4).

Molecular Weight: Predicted: 301 kDa

Observed: 280 kDa

Gene ID: 10178

NCBI Accession: NP_001156750

UniProt: Q9UKZ4

Pathways: Regulation of Actin Filament Polymerization