SLC29A3 antibody (N-Term)

Catalog No. ABIN6992117

Product Details anti-SLC29A3 Antibody

Target: SLC29A3 (Solute Carrier Family 29 Member 3 (SLC29A3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC29A3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificity: SLC29A3 antibody is human, mouse and rat reactive. At least two isoforms of SLC29A3 are known to exist, this antibody will detect both isoforms. SLC29A3 antibody is predicted to not cross-react with other SLC29 proteins.

Purification: SLC29A3 antibody is affinity chromatography purified via peptide column.

Immunogen: SLC29A3 antibody was raised against a 19 amino acid peptide near the amino terminus of human SLC29A3. The immunogen is located within the first 50 amino acids of SLC29A3.

Isotype: IgG

Application Details

Application Notes: SLC29A3 antibody can be used for detection of SLC29A3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: SLC29A3 antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: SLC29A3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for SLC29A3

Target: SLC29A3 (Solute Carrier Family 29 Member 3 (SLC29A3))

Alternative Name: SLC29A3 (SLC29A3 Products)

Synonyms: ENT3 antibody, HCLAP antibody, HJCD antibody, PHID antibody, Ent3 antibody, 4933435C21Rik antibody, AW987637 antibody, solute carrier family 29 member 3 antibody, solute carrier family 29 (nucleoside transporters), member 3 antibody, SLC29A3 antibody, Slc29a3 antibody

Background: SLC29A3 is a member of the equilibrative nucleoside transporter family which plays a key role in nucleoside and nucleobase uptake for salvage pathways of nucleotide synthesis (1,2). SLC29A3 is a transmembrane glycoprotein that localizes to the lysosomal membrane and is a broad selectivity, low affinity nucleoside transporter (3). Mutations in the SLC29A3 gene have been associated with H syndrome, which is characterized by cutaneous hyperpigmentation and hypertrichosis, hepatosplenomegaly, heart anomalies, and hypogonadism (4). A related disorder, PHID (pigmented hypertrichosis with insulin-dependent diabetes mellitus), has also been associated with mutations at this locus (5).

Molecular Weight: Predicted: 52 kDa

Observed: 51 kDa

Gene ID: 55315

NCBI Accession: NP_060814

UniProt: Q9BZD2