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Neuroligin 2 antibody (C-Term)

NLGN2 Reactivity: Human, Rat, Mouse WB, ELISA, IF, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6992063
  • Target See all Neuroligin 2 (NLGN2) Antibodies
    Neuroligin 2 (NLGN2)
    Binding Specificity
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 630-680, C-Term
    Reactivity
    • 9
    • 8
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    Human, Rat, Mouse
    Host
    • 8
    • 2
    Rabbit
    Clonality
    • 10
    Polyclonal
    Conjugate
    • 7
    • 1
    • 1
    • 1
    This Neuroligin 2 antibody is un-conjugated
    Application
    • 7
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    NLGN2 antibody is human, mouse and rat reactive. At least two isoforms are known to exist, this antibody will detect both isoforms. NLGN2 antibody is predicted to not cross-react with other members of the NLGN protein family.
    Purification
    NLGN2 antibody is affinity chromatography purified via peptide column.
    Immunogen
    NLGN2 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human NLGN2. The immunogen is located within amino acids 630 - 680 of NLGN2.
    Isotype
    IgG
    Top Product
    Discover our top product NLGN2 Primary Antibody
  • Application Notes
    NLGN2 antibody can be used for detection of NLGN2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    NLGN2 antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    NLGN2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • Target
    Neuroligin 2 (NLGN2)
    Alternative Name
    NLGN2 (NLGN2 Products)
    Synonyms
    Nlgn2 antibody, GB10066 antibody, NLGN2 antibody, CCE-L2 antibody, NV50031 antibody, Nv123771 antibody, NL2 antibody, RP23-422L16.24 antibody, neuroligin 2 antibody, LOC410779 antibody, NLGN2 antibody, LOC663865 antibody, LOC100123771 antibody, Nlgn2 antibody
    Background
    Neuroligin 2 (NLGN2) is a member of a family of neuronal cell surface proteins that localize to the post-synaptic membrane (1,2). Neuroligins are thought to act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses (2). NLGN2 has been shown to control perisomatic inhibitory synapse maturation together with gephyrin and collybistin, thereby regulating GABA receptor clustering on neurons (3,4). NLGN2 also exhibits differential functions at different types of inhibitory synapses on the same postsynaptic neuron (5).
    Molecular Weight
    Predicted: 92, 99 kDa

    Observed: 80, 97 kDa
    Gene ID
    57555
    NCBI Accession
    NP_065846
    UniProt
    Q8NFZ4
    Pathways
    Cell-Cell Junction Organization, Synaptic Membrane
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