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LIN54 antibody (C-Term)

LIN54 Reactivity: Human, Rat, Mouse WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6992048
  • Target See all LIN54 Antibodies
    LIN54 (Lin-54 Homolog (LIN54))
    Binding Specificity
    • 2
    • 2
    • 2
    • 1
    C-Term
    Reactivity
    • 8
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    Human, Rat, Mouse
    Host
    • 8
    Rabbit
    Clonality
    • 8
    Polyclonal
    Conjugate
    • 8
    This LIN54 antibody is un-conjugated
    Application
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    LIN54 antibody is human, mouse, and rat reactive. Multiple isoforms of LIN54 are known to exist.
    Purification
    LIN54 antibody is affinity chromatography purified via peptide column.
    Immunogen
    LIN54 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human LIN54. The immunogen is located within the last 50 amino acids of LIN54.
    Isotype
    IgG
    Top Product
    Discover our top product LIN54 Primary Antibody
  • Application Notes
    LIN54 antibody can be used for detection of LIN54 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL

    Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    LIN54 antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    LIN54 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • Target
    LIN54 (Lin-54 Homolog (LIN54))
    Alternative Name
    LIN54 (LIN54 Products)
    Synonyms
    CXCDC1 antibody, JC8.6 antibody, MIP120 antibody, 4832414L08 antibody, AI461788 antibody, mKIAA2037 antibody, RGD1311361 antibody, lin-54 DREAM MuvB core complex component antibody, lin-54 homolog (C. elegans) antibody, LIN54 antibody, Lin54 antibody
    Background
    LIN54 is a component of the LIN, or DREAM, complex, an essential regulator of cell cycle genes. This complex functions as a transcriptional repressor by binding to promoters of E2F target genes that regulate the G1/S transition (1). LIN54 is required for cell cycle progression and can bind to the cdc2 promoter in a sequence-specific manner (2).
    Molecular Weight
    Predicted: 88 kDa

    Observed: 82 kDa
    Gene ID
    132660
    NCBI Accession
    NP_919258
    UniProt
    Q6MZP7
    Pathways
    Cell Division Cycle, Mitotic G1-G1/S Phases
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