SOX18 antibody (N-Term)

Catalog No. ABIN6992041

Product Details anti-SOX18 Antibody

Target: SOX18 (SRY (Sex Determining Region Y)-Box 18 (SOX18))

Binding Specificity: AA 40-90, N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX18 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: SOX18 antibody is human, mouse and rat reactive. SOX18 is predicted to not cross-react with other SOX proteins.

Purification: SOX18 antibody is affinity chromatography purified via peptide column.

Immunogen: SOX18 antibody was raised against a 17 amino acid peptide near the amino terminus of human SOX18. The immunogen is located within amino acids 40 - 90 of SOX18.

Isotype: IgG

Application Details

Application Notes: SOX18 antibody can be used for detection of SOX18 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: SOX18 antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: SOX18 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for SOX18

Target: SOX18 (SRY (Sex Determining Region Y)-Box 18 (SOX18))

Alternative Name: SOX18 (SOX18 Products)

Synonyms: HLTS antibody, AI385749 antibody, Ra antibody, Ragl antibody, sox18 antibody, xSox18alpha antibody, xSox18beta antibody, xsox18 antibody, SRY-box 18 antibody, SRY (sex determining region Y)-box 18 antibody, SRY box 18 antibody, SRY-box 18 S homeolog antibody, SRY-box 18 L homeolog antibody, SRY box 1 antibody, SOX18 antibody, Sox18 antibody, sox18.S antibody, sox18.L antibody, Sox1 antibody

Background: SOX18 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate (1,2). SOX18 is part of the SoxF subgroup which plays an important role in the differentiation of different cell types (3). SOX is known to be involved with vascularization and endothelial development, suggesting that it may be useful as a potential target for inhibiting tumor angiogenesis (4). Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia (5).

Molecular Weight: Predicted: 42 kDa

Observed: 44 kDa

Gene ID: 54345

NCBI Accession: NP_060889

UniProt: P35713