POU2F3 antibody (C-Term)

Catalog No. ABIN6992005

Product Details anti-POU2F3 Antibody

Target: POU2F3 (POU Class 2 Homeobox 3 (POU2F3))

Binding Specificity: AA 370-420, C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POU2F3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: POU2F3 antibody is human, mouse and rat reactive. At least two isoforms are known to exist. This antibody will recognize both isoforms. POU2F3 antibody is predicted to not cross-react with other members of the POU domain class 2 family.

Purification: POU2F3 antibody is affinity chromatography purified via peptide column.

Immunogen: POU2F3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human POU2F3. The immunogen is located within amino acids 370 - 420 of POU2F3.

Isotype: IgG

Application Details

Application Notes: POU2F3 antibody can be used for detection of POU2F3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: POU2F3 antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: POU2F3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for POU2F3

Target: POU2F3 (POU Class 2 Homeobox 3 (POU2F3))

Alternative Name: POU2F3 (POU2F3 Products)

Synonyms: POU2F3 antibody, zgc:136377 antibody, zgc:158534 antibody, Epoc-1 antibody, OCT-11 antibody, OCT11 antibody, OTF-11 antibody, PLA-1 antibody, PLA1 antibody, Skn-1a antibody, nrl-16 antibody, nrl16-A antibody, Oct-11a antibody, Oct11 antibody, Otf-11 antibody, Otf11 antibody, Skin antibody, Skin-1a antibody, Skn-li antibody, POU class 2 homeobox 3 antibody, POU class 2 homeobox 3 L homeolog antibody, POU domain, class 2, transcription factor 3 antibody, POU2F3 antibody, pou2f3 antibody, Pou2f3 antibody, pou2f3.L antibody

Background: POU2F3, also known as Epoc-1, is a member of a family of POU domain family of transcription factors (1). POU2F3 is expressed primarily in the epidermis and plays a critical role in keratinocyte proliferation and differentiation (1,2). It is a crucial transcription factor that is required for the development of sweet, umami, and bitter, but not sour taste receptor cells (3). POU2F3 is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer (4).

Molecular Weight: Predicted: 48 kDa

Observed: 55 kDa

Gene ID: 25833

NCBI Accession: NP_001231611

UniProt: Q9UKI9