GLIPR1L2 antibody (AA 120-170)

Catalog No. ABIN6991951

Product Details anti-GLIPR1L2 Antibody

Target: GLIPR1L2 (GLI Pathogenesis-Related 1 Like 2 (GLIPR1L2))

Binding Specificity: AA 120-170

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLIPR1L2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: GLIPR1L2 antibody is human specific. At least two isoforms of GLIPR1L2 are known to exist, this antibody will detect both isoforms. This antibody is predicted to not cross-react with other GLIPR or GLIPR-like proteins.

Purification: GLIPR1L2 antibody is affinity chromatography purified via peptide column.

Immunogen: GLIPR1L2 antibody was raised against an 15 amino acid peptide near the center of human GLIPR1L2. The immunogen is located within amino acids 120 - 170 of GLIPR1L2.

Isotype: IgG

Application Details

Application Notes: GLIPR1L2 antibody can be used for detection of GLIPR1L2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: GLIPR1L2 antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: GLIPR1L2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for GLIPR1L2

Target: GLIPR1L2 (GLI Pathogenesis-Related 1 Like 2 (GLIPR1L2))

Alternative Name: GLIPR1L2 (GLIPR1L2 Products)

Synonyms: 4921508O11Rik antibody, GLI pathogenesis related 1 like 2 antibody, GLI pathogenesis-related 1 like 2 antibody, GLIPR1L2 antibody, Glipr1l2 antibody

Background: The GLIPR1-like 2 protein (GLIPR1L2) gene is part of a p53 target gene cluster that includes the related proteins GLIPR1 and GLIPR1L2 (2). GLIPR1L2 is similar to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family (1). GLIPR1 is a tumor suppressor whose expression is regulated by p53 (3). Deletions of the GLIPR1/GLIPR1L1/GLIPR1L2 gene cluster have been observed in some multiple myeloma samples, suggesting that these proteins may also be involved in the pathogenesis of multiple myeloma (4).

Molecular Weight: Predicted: 28, 31, 38 kDa

Observed: 28 kDa

Gene ID: 144321

NCBI Accession: NP_001257325

UniProt: Q4G1C9