TMIGD1 antibody (AA 150-200)

Catalog No. ABIN6991945

Product Details anti-TMIGD1 Antibody

Target: TMIGD1 (Transmembrane and Immunoglobulin Domain Containing 1 (TMIGD1))

Binding Specificity: AA 150-200

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMIGD1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificity: TMIGD1 antibody is human, mouse and rat reactive. At least two isoforms of TMIGD1 are known to exist, this antibody will detect both isoforms.

Purification: TMIGD1 antibody is affinity chromatography purified via peptide column.

Immunogen: TMIGD1 antibody was raised against an 18 amino acid peptide near the center of human TMIGD1. The immunogen is located within amino acids 150 - 200 of TMIGD1.

Isotype: IgG

Application Details

Application Notes: TMIGD1 antibody can be used for detection of TMIGD1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: TMIGD1 antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: TMIGD1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for TMIGD1

Target: TMIGD1 (Transmembrane and Immunoglobulin Domain Containing 1 (TMIGD1))

Alternative Name: TMIGD1 (TMIGD1 Products)

Synonyms: RGD1307444 antibody, Tmigd antibody, TMIGD antibody, UNQ9372 antibody, 2010002A20Rik antibody, transmembrane and immunoglobulin domain containing 1 antibody, Tmigd1 antibody, TMIGD1 antibody

Background: TMIGD1 (transmembrane and immunoglobulin domain containing 1) is a 262 amino acid single-pass membrane protein that contains two Ig-like C2-type (immunoglobulin-like) domains (1,2). It is a nonsecreted, glycosylated protein located in the cytoplasm and cell membrane (1). TMIGD1 might be a possible cell-differentiation marker in the intestine, whose expression is lost during cellular transformation and promote progression of tumorigenesis in the intestinal epithelium (2-4). TMIGD1 has also been postulated to play a role in cell adhesion (2).

Molecular Weight: Predicted: 29 kDa

Observed: 24 kDa

Gene ID: 388364

NCBI Accession: NP_996663

UniProt: Q6UXZ0